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Giuseppe Berton MD FESC, Rocco Cordiano MD, Rosa Palmieri MD, Giuseppe Gheno MD, Paolo Mormino MD, Paolo Palatini MD

 

BACKGROUND: Elevated heart rate (HR) has been found to be related to an increased death rate in patients with acute myocardial infaretion (AMI), but sex differences and optimal timing for HR measurement have not been sufficiently investi. gateld.
OBJECTIVES: To verify the predictive value of HR for one-year mortality in a cohort of subjects huspitalized for AMI, with men and women considered separately.
PATIENTS AND METHODS: HR was measured in 424 patients (303 men and 121 women) with constant sinus HR, on the first, third and seventh days after hospital admission for AMI. Clinical and laboratory data were obtained on the same days. AIl patients were followed up for one vear.
RESULTS: Among the men, the one-year mortality rate was 5% for the subjects with a seven-day HR of less than 80 beats/min, and the one-year mortality rate was 39% for patients with a seven-
day HR of 80 beats/min or more (P<0.0001). Among the women, the differences in mortality related to HR were not significant. In a multivariate Cox regression analysis, the relative risks of mor- tality in men who had an HR of 80 beats/min or more were 3.1 (CI=1.4 to 7.0, P=0.003) on the first day, 4.1 (CI=1.8 to 9.8, P=0.001) on the third day and 8.6 (CI=2.9 to 27.0, P<0.0001) on the seventh day. In the 203 men in whom echocardiographic left ventricular ejection fraction was measured, an interactive effect of high HR with depressed ejection fraction on mortality was found. Beta-blocking therapy influenced HR during AMI but did not influence the HR-mortality association.
CONCLUSIONS: The results of the present prospective study show that HR measured during the first week after admission for AMI is an important predictor of mortality in men. The predic- tive power of HR increased from the first to the seventh day after AMI

The Canadian J. Cardiology, May 2002, 18:495-502.

 

Key Words: Autonomie nervous system; Heart rate; Mortality; Myocardial infarction; Sex

 

 

Welcome

In 1992, a small group of medical researchers and other participants embarked on an project to investigate new clinical factors for heart disease, studying patients with acute coronary syndrome and following them for many years. Today, the observations on the long-term survival after acute coronary syndrome are internationally acknowledged. Main results appears on the most important cardiovascular texts across the world. The study is called “the ABC heart disease study”.
Nel 1992, un piccolo gruppo di medici ricercatori ed altri operatori sanitari, iniziarono un progetto per studiare nuovi fattori clinici della malattia cardiaca, studiando pazienti con sindrome coronarica acuta e seguendoli per molti anni. Oggi, ciò che è stato osservato sulla sopravvivenza a lungo temine dopo sindrome coronarica acuta è riconosciuto a livello internazionale. I principali risultati appaiono sui maggiori testi di medicina cardiovascolare in tutto il mondo. Questo progetto è stato chiamato “the ABC heart disease study”.

Autori coordinatori  Campi di interesse

 

Mission

The Mission of the ABC Study on Heart Disease Project is to promote the knowledge on heart disease chiefly based on the long-term follow up of the patients. And to promote citizen health supporting preventive, social, and sport activities.
 

First 3 years results of the study

Malattia cardiaca e neoplasia: i risultati dei primi 3 anni di studio
Heart disease and neoplasia: first 3 years results of the study

 Risultati Terzo Anno

I risultati del Terzo Anno di lavoro del Progetto regionale

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Under the patronage of

Conegliano - TV (Italy)        Farra di Soligo (TV)    Comune di Bassano del Grappa    ULSS5 Logo   ULSS7 Logo ULSS2 LogoU.S.ACLI Associazione Amici del Cuore Bassano Amici Riabilitazione Cardiopatici Marostica ARIS onlus logo   E20RUN Conegliano  CRT Cimavilla Running Team - logo

Un ringraziamento per il supporto continuativo dal 2015 ad ABC Study Association

Banca della Marca

 

Riconoscimenti - Acknowlegments

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